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Where R can be any number of chemical groups including the two active forms of vitamin B12, adenosyl and methyl B12, but also a myriad of inactive groups, such as hydroxycobalamin, cyanocobalamin, nitrosylcobalamin, cysteinylcobalamin, glutathionylcobalamin, Co(II)cobalamin, aquocobalamin, chlorocobalamin, sulfitocobalamin, thiocyantocobalamin, homocysteinylcobalamin amongst others (Hannibal et al, 2008)