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Single Amino Acid Supplementation in Inherited Metabolic Disorders: An Evidence-Based Review of Interventions

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Its primary proposed target is nicotinamide N-methyltransferase (NNMT), an enzyme that transfers a methyl group from S-adenosylmethionine (SAM) to nicotinamide, producing 1-methylnicotinamide and S-adenosylhomocysteine (SAH)